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KMID : 1142720180210030064
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Annals of Clinical Microbiology
2018 Volume.21 No. 3 p.64 ~ p.67
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Nocardia abscessus Cutaneous Abscess: A Case Report and Review of the Literature
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Park Hee-Sue
Son Bo-Ra
Song Min-Suk
Shin Kyeong-Seob
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Abstract
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We describe a cutaneous abscess caused by Nocardia abscessus in a previously healthy woman. A 74- year-old woman presented with recurrent bullae on her left forearm that developed 1 week prior and was initially suspected to be a cutaneous infection with Mycobacteria or Tinea corporis. Histopathologically, the skin lesion formed an abscess. A smear revealed a few branched Gram-positive filamentous microorganisms that formed a creamy white colony on a blood agar plate after incubation for 3 days. The colony tested negative on acid-fast bacilli (AFB) staining, but was positive on modified AFB staining. The isolate was confirmed to be N. abscessus by 16S rRNA sequencing analysis. The isolate was susceptible to trimethoprim-sulfamethoxazole, amikacin, cefotaxime and erythromycin but resistant to penicillin. The patient was treated with clarithromycin but subsequently lost to follow-up. To the best of our knowledge, this is the first report of a human cutaneous infection with N. abscessus in Korea.
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KEYWORD
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Cutaneous abscess, Nocardia abscessus, 16S rRNA sequence
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